Top Python Repositories

The most popular Python repositories on GitHub, ranked by stars, forks, and contributors.

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1

A collectively curated list of free public APIs for software and web development. This extensive repository contains thousands of APIs across 100+ categories including animals, finance, health, music, news, science, sports, weather, and more. Maintained by the community and APILayer team.

Python
2 days ago
2

A collaborative, multilingual collection of freely available programming books, courses, podcasts, and interactive tutorials. Maintained by the Free Ebook Foundation, it indexes thousands of learning resources across numerous programming languages and computer science topics.

Python
3 days ago
3

A comprehensive, open-source guide to mastering large-scale system design. Covers scalability, CAP theorem, databases, caching, load balancing, and more, with real-world architectures, interview questions with solutions, and Anki flashcards for effective spaced-repetition learning.

Python
5 months ago
4

A curated list of awesome Python frameworks, libraries, software and resources. Covers web frameworks, data analysis, machine learning, testing, and more.

Python
2 days ago
5

A curated list of programming tutorials where developers learn to build applications from scratch. Organized by primary programming languages, covering topics like compilers, operating systems, databases, and web apps through hands-on projects.

Python
4 days ago
6

A self-improving AI agent by Nous Research with a built-in learning loop — it creates skills from experience, autonomously improves them during use, and deepens a user model across sessions. Connect via CLI, Telegram, Discord, Slack, WhatsApp, or Signal. Supports 300+ models (OpenAI, Anthropic, Gemini, etc.), 40+ tools, cron scheduling, subagent delegation, and runs anywhere from a $5 VPS to serverless GPU clusters.

Python
2 hours ago
7

A comprehensive collection of algorithms implemented in Python for educational purposes. Covers sorting, searching, data structures, machine learning, cryptography, and more to help developers learn and understand algorithmic concepts.

Python
3 days ago
8

AutoGPT is a powerful platform for building, deploying, and managing autonomous AI agents. It enables users to create custom agents, automate complex workflows, and leverage pre-built agents for tasks like content generation and social media management.

Python
4 hours ago
9

yt-dlp is a feature-rich command-line audio/video downloader supporting thousands of sites. A fork of youtube-dl, it offers enhanced performance, format sorting, SponsorBlock integration, and support for extracting content from YouTube, Bilibili, TikTok, and more.

Python
2 days ago
10

Microsoft's lightweight Python tool that converts PDF, Word, Excel, PowerPoint, images, audio, HTML, and more into Markdown — preserving headings, tables, and links. Designed for LLM and RAG pipelines, with CLI/Python API, MCP server for AI agents, plugin extensibility, and optional Azure cloud and LLM-powered OCR.

Python
8 days ago
11

HelloGitHub is a monthly publication sharing interesting and beginner-friendly open-source projects on GitHub. Updated on the 28th of each month, it features practical projects, tutorials, books, and enterprise-level projects across multiple programming languages, helping developers quickly discover the charm of open source.

Python
5 days ago
12

Anthropic's official repository of skills for Claude. Contains ready-to-use skills for creative tasks, technical workflows, enterprise applications, and document processing. Learn how to build custom skills to extend Claude's capabilities for specialized tasks.

Python
13 days ago
13

A feature-rich web UI for Stable Diffusion, enabling text-to-image, image-to-image, outpainting, and inpainting. Supports extensions, LoRA, custom embeddings, and API access with a user-friendly Gradio interface.

Python
5 months ago
14

Transformers is the model-definition framework for state-of-the-art machine learning with text, vision, audio, video, and multimodal models. It provides over 1M+ pretrained checkpoints on the Hugging Face Hub for easy inference and training.

Python
20 hours ago
15

Langflow is a powerful platform for building and deploying AI-powered agents and workflows. It offers a visual builder, API/MCP server deployment, multi-agent orchestration, and supports all major LLMs and vector databases.

Python
2 days ago
16

Open WebUI is an extensible, feature-rich, and user-friendly self-hosted AI platform designed to operate entirely offline. It supports various LLM runners like Ollama and OpenAI-compatible APIs, with built-in inference engine for RAG, making it a powerful AI deployment solution.

Python
a day ago
17

LangChain is a framework for building agents and LLM-powered applications. It helps chain together interoperable components and third-party integrations to simplify AI application development while future-proofing decisions as technology evolves.

Python
21 hours ago
18

youtube-dl is a command-line program to download videos from YouTube.com and many other video platforms. It supports Python 2.6+, 3.2+, works cross-platform on Unix, Windows, and macOS, and is released into the public domain.

Python
6 months ago
19

Anthropic's official agentic coding tool that runs in your terminal and IDE. Understands your codebase and helps you code faster through natural language — from editing files and explaining complex code to automating git workflows, reviewing PRs, and orchestrating multi-agent tasks. Supports plugins, MCP servers, and dynamic workflows.

Python
20 hours ago
20

A curated cookbook of 100+ ready-to-run AI Agent & RAG applications — from single-file starter agents to multi-agent teams, voice AI, MCP agents, and generative UI. Clone, customize, and ship with any LLM provider including Claude, Gemini, OpenAI, Llama, and more.

Python
4 days ago