Top Python Repositories

The most popular Python repositories on GitHub, ranked by stars, forks, and contributors.

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1

A collectively curated list of free public APIs for software and web development. This extensive repository contains thousands of APIs across 100+ categories including animals, finance, health, music, news, science, sports, weather, and more. Maintained by the community and APILayer team.

Python
3 days ago
2

A collaborative, multilingual collection of freely available programming books, courses, podcasts, and interactive tutorials. Maintained by the Free Ebook Foundation, it indexes thousands of learning resources across numerous programming languages and computer science topics.

Python
a day ago
3

Learn how to design large-scale systems. Prep for the system design interview. An organized collection of resources covering scalability, performance, availability, and common system design patterns with solutions and Anki flashcards.

Python
3 months ago
4

A curated list of awesome Python frameworks, libraries, software and resources. Covers web frameworks, data analysis, machine learning, testing, and more.

Python
11 days ago
5

A comprehensive collection of algorithms implemented in Python for educational purposes. Covers sorting, searching, data structures, machine learning, cryptography, and more to help developers learn and understand algorithmic concepts.

Python
4 days ago
6

A self-improving AI agent by Nous Research with a built-in learning loop — it creates skills from experience, autonomously improves them during use, and deepens a user model across sessions. Connect via CLI, Telegram, Discord, Slack, WhatsApp, or Signal. Supports 300+ models (OpenAI, Anthropic, Gemini, etc.), 40+ tools, cron scheduling, subagent delegation, and runs anywhere from a $5 VPS to serverless GPU clusters.

Python
4 hours ago
7

AutoGPT is a powerful platform for building, deploying, and managing autonomous AI agents. It enables users to create custom agents, automate complex workflows, and leverage pre-built agents for tasks like content generation and social media management.

Python
13 hours ago
8

yt-dlp is a feature-rich command-line audio/video downloader supporting thousands of sites. A fork of youtube-dl, it offers enhanced performance, format sorting, SponsorBlock integration, and support for extracting content from YouTube, Bilibili, TikTok, and more.

Python
2 days ago
9

A feature-rich web UI for Stable Diffusion, enabling text-to-image, image-to-image, outpainting, and inpainting. Supports extensions, LoRA, custom embeddings, and API access with a user-friendly Gradio interface.

Python
4 months ago
10

HelloGitHub is a monthly publication sharing interesting and beginner-friendly open-source projects on GitHub. Updated on the 28th of each month, it features practical projects, tutorials, books, and enterprise-level projects across multiple programming languages, helping developers quickly discover the charm of open source.

Python
25 days ago
11

Transformers is the model-definition framework for state-of-the-art machine learning with text, vision, audio, video, and multimodal models. It provides over 1M+ pretrained checkpoints on the Hugging Face Hub for easy inference and training.

Python
21 hours ago
12

Microsoft's lightweight Python tool that converts PDF, Word, Excel, PowerPoint, images, audio, HTML, and more into Markdown — preserving headings, tables, and links. Designed for LLM and RAG pipelines, with CLI/Python API, MCP server for AI agents, plugin extensibility, and optional Azure cloud and LLM-powered OCR.

Python
a month ago
13

Anthropic's official repository of skills for Claude. Contains ready-to-use skills for creative tasks, technical workflows, enterprise applications, and document processing. Learn how to build custom skills to extend Claude's capabilities for specialized tasks.

Python
13 days ago
14

Langflow is a powerful platform for building and deploying AI-powered agents and workflows. It offers a visual builder, API/MCP server deployment, multi-agent orchestration, and supports all major LLMs and vector databases.

Python
17 hours ago
15

Open WebUI is an extensible, feature-rich, and user-friendly self-hosted AI platform designed to operate entirely offline. It supports various LLM runners like Ollama and OpenAI-compatible APIs, with built-in inference engine for RAG, making it a powerful AI deployment solution.

Python
3 hours ago
16

youtube-dl is a command-line program to download videos from YouTube.com and many other video platforms. It supports Python 2.6+, 3.2+, works cross-platform on Unix, Windows, and macOS, and is released into the public domain.

Python
4 months ago
17

LangChain is a framework for building agents and LLM-powered applications. It helps chain together interoperable components and third-party integrations to simplify AI application development while future-proofing decisions as technology evolves.

Python
8 hours ago
18

Anthropic's official agentic coding tool that runs in your terminal and IDE. Understands your codebase and helps you code faster through natural language — from editing files and explaining complex code to automating git workflows, reviewing PRs, and orchestrating multi-agent tasks. Supports plugins, MCP servers, and dynamic workflows.

Python
2 days ago
19

The most powerful and modular visual AI engine for designing and executing advanced stable diffusion pipelines using a graph/nodes/flowchart interface. Available on Windows, Linux, and macOS with support for image, video, audio, and 3D generation models.

Python
10 hours ago
20

A curated collection of awesome LLM apps built with RAG, AI Agents, Multi-agent Teams, MCP, Voice Agents, and more. Features apps using OpenAI, Anthropic, Google, xAI, and open-source models like Llama and Qwen that can run locally.

Python
8 days ago